Search | Engineering

订阅投稿

首页工程期刊工程焦点工程成就工程前沿关于我们 English

资源类型

期刊论文 933

年份

2024 1

2023 59

2022 48

2021 48

2020 59

2019 38

2018 60

2017 56

2016 42

2015 39

2014 31

2013 37

2012 32

2011 33

2010 59

2009 48

2008 24

2007 28

2006 12

2005 21

展开︾

关键词

关键技术 17

颠覆性技术 16

技术 14

技术预见 11

发展趋势 8

工程科技 8

三峡工程 7

战略研究 7

施工技术 7

2035年 6

信息技术 6

技术创新 6

2035 5

发展战略 5

施工 5

勘探开发 4

升船机 4

工程 4

技术体系 4

展开︾

检索范围：

排序：展示方式：

Microfluidic synthesis of renewable biosorbent with highly comprehensive adsorption performance for copper

Yong Zhu, Zhishan Bai, Bingjie Wang, Linlin Zhai, Wenqiang Luo

《化学科学与工程前沿（英文）》 2017年第11卷第2期页码 238-251 doi: 10.1007/s11705-017-1627-1

摘要： A microsphere biosorbent with uniform size (CV= 1.52%), controllable morphology and component, and high mechanical strength was synthesized from chitosan by microfluidic technology combining with chemical crosslinking and solvent extraction. This chitosan microsphere (CS-MS) was prepared with a two-step solidification process, which was acquired by drying for the enhancement of mechanical property in final. The adsorption behavior of CS-MS towards copper (II) and main influencing factors on adsorption performance were investigated by batch experiments. Kinetic data highlighted dominant chemical bonding along with electrons transferring in adsorption process. Isothermal analysis indicated that adsorption capacity was relevant to the number of active site. All these explorations provided a new direction for preparing highly comprehensive performance sorbent used in heavy metal treatment via microfluidic technology.

关键词： chitosan microsphere microfluidic technology adsorption copper (II)

HTML PDF 收藏

Synthesis of crystals and particles by crystallization and polymerization in droplet-based microfluidic

Jingtao WANG, Jin ZHANG, Junjie HAN,

《化学科学与工程前沿（英文）》 2010年第4卷第1期页码 26-36 doi: 10.1007/s11705-009-0292-4

摘要： The recent advances in crystallization and polymerization assisted by droplet-based microfluidics to synthesize micro-particles and micro-crystals are reviewed in this paper. Droplet-based microfluidic devices are powerful tools to execute some precise controls and operations on the flow inside microchannels by adjusting fluid dynamics parameters to produce monodisperse emulsions or multiple-emulsions of various materials. Major features of this technique are producing particles of monodispersity to control the shape of particles in a new level, and to generate droplets of diverse materials including aqueous solutions, gels and polymers. Numerous microfluidic devices have been employed to generate monodisperse droplets of range from nm to μm, such as T junctions, flow-focusing devices and co-flow or cross-flow capillaries. These discrete, independently controllable droplets are ideal microreactors to be manipulated in the channels to synthesize the nanocrystals, protein crystals, polymer particles and microcapsules. The generated monodisperse particles or crystals are to meet different technical demands in many fields, such as crystal engineering, encapsulation and drug delivery systems. Microfluidic devices are promising tools in the synthesis of micron polymer particles that have diverse applications such as the photonic materials, ion-exchange and chromatography columns, and field-responsive rheological fluids. Processes assisted by microfluidic devices are able to produce the polymer particles (including Janus particles) with precise control over their sizes, size distribution, morphology and compositions. The technology of microfluidics has also been employed to generate core-shell microcapsules and solid microgels with precise controlled sizes and inner structures. The chosen “smart” materials are sensitive to an external stimulus such as the change of the pH, electric field and temperature. These complex particles are also able to be functionalized by encapsulating nanoparticles of special functions and by attaching some special groups like targeting ligands. The nucleation kinetics of some crystals like KNO was investigated in different microfluidic devices. Because of the elimination of the interactions among crystallites in bulk systems, using independent droplets may help to measure the nucleation rate more accurately. In structural biology, the droplets produced in microfluidic devices provide ideal platforms for protein crystallization on the nanoliter scale. Therefore, they become one of the promising tools to screen the optimal conditions of protein crystallization.

关键词： core-shell monodisperse nucleation Microfluidic different technical

HTML PDF 收藏

A review on emulsification via microfluidic processes

Yichen Liu, Yongli Li, Andreas Hensel, Juergen J. Brandner, Kai zhang, Xiaoze Du, Yongping Yang

《化学科学与工程前沿（英文）》 2020年第14卷第3期页码 350-364 doi: 10.1007/s11705-019-1894-0

摘要： Emulsion is a disperse system with two immiscible liquids, which demonstrates wide applications in diverse industries. Emulsification technology has advanced well with the development of microfluidic process. Compared to conventional methods, the microfluidics-based process can produce controllable droplet size and distribution. The droplet formation or breakup is the result of combined effects resulting from interfacial tension, viscous, and inertial forces as well as the forces generated due to hydrodynamic pressure and external stimuli. In the current study, typical microfluidic systems, including microchannel array, T-shape, flow-focusing, co-flowing, and membrane systems, are reviewed and the corresponding mechanisms, flow regimes, and main parameters are compared and summarized.

关键词： microfluidics emulsification capillary number droplet breakup

HTML PDF 收藏

Microfluidic production of liposomes through liquid–liquid phase separation in ternary droplets

《化学科学与工程前沿（英文）》 2022年第16卷第6期页码 1017-1022 doi: 10.1007/s11705-021-2118-y

摘要： Liposomes, the self-assembled phospholipid vesicles, have been extensively used in various fields such as artificial cells, drug delivery systems, biosensors and cosmetics. However, current microfluidic routes to liposomes mostly rely on water-in-oil-in-water double emulsion droplets as templates, and require complex fabrication of microfluidic devices, and tedious manipulation of multiphase fluids. Here we present a simple microfluidic approach to preparing monodisperse liposomes from oil-in-water droplets. For demonstration, we used butyl acetate-water-ethanol ternary mixtures as inner phase and an aqueous solution of surfactants as outer phase to make oil-in-water droplets, which can evolve into water-in-oil-in-water double emulsion droplets by liquid–liquid phase separation of ternary mixtures. Subsequently, the resultant water-in-oil-in-water droplets underwent a dewetting transition to form separated monodisperse liposomes and residual oil droplets, with the assistance of surfactants. The method is simple, does not require complex microfluidic devices and tedious manipulation, and provides a new platform for controllable preparation of liposomes.

关键词： microfluidics liposomes ternary droplets phase separation

HTML PDF 收藏

deposition during crossflow filtration as influenced by permeate flux and crossflow velocity using a microfluidic

Hongzhan Di, Gregory J. O. Martin, Dave E. Dunstan

《化学科学与工程前沿（英文）》 2021年第15卷第3期页码 552-561 doi: 10.1007/s11705-020-1962-5

摘要： Particle deposition during crossflow filtration is significantly influenced by the operating conditions, in particular the permeate flux and crossflow velocity. However, there is a lack of detailed knowledge about how deposit layer structures and distributions depend on operating parameters. This study uses a microfluidic visualisation filtration system to examine the influence of operating conditions on the deposition process during crossflow ultrafiltration from a microscopic perspective. Increasing the permeate flux caused an increasing amount of deposition and a thicker deposit layer. Higher crossflow velocities reduced the extent of deposition. The degree of deposition varied over a range of operating conditions due to the altered hydrodynamic forces exerted on the particles, which can be examined by the deposition probability according to an existing model. Building on this, an empirical correlation between the deposition probability and volume of deposition as function of filtration time was developed, which gave good agreement with experimental results. The effect of solution conditions was also involved in this correlation as a interaction energies. This could be useful for predicting the dynamic deposition process during crossflow filtration over a range of operating and solution conditions.

关键词： particle deposition crossflow filtration microfluidics confocal microscopy

HTML PDF 收藏

基于集成液体交换的微流控芯片的完整单细胞动态变形测量 Article

Xu Du, Di Chang, Shingo Kaneko, Hisataka Maruyama, Hirotaka Sugiura, Masaru Tsujii, Nobuyuki Uozumi, Fumihito Arai

《工程（英文）》 2023年第24卷第5期页码 94-101 doi: 10.1016/j.eng.2022.08.020

摘要：

本文报道了采用一种集成了力感应和液体交换功能的微流控芯片来测量单细胞力学性能的方法。使用光学镊子操纵和定位在推力探针和力传感器探针之间的单个细胞。这两个芯片上的探针被设计用来捕获和使细胞变形。通过移动由外力驱动的推力探针，而使单个细胞变形。层流在探针之间形成液-液界面以改变细胞外环境。通过控制注入压力来改变界面的位置。通过调整两个正压力和一个负压力来平衡流动的扩散和扰动。在微流控芯片中测定了不同渗透浓度环境下的单个集胞藻（Synechocystis）菌株PCC 6803 的力学性能。在0.3~0.7 s 内实现液体交换过程，同时也显示了单个细胞的动态变形。可以在30 s 内收集不同渗透浓度下两个杨氏模量值的测量结果以及单个细胞在渗透压冲击下的动态响应。研究了野生型（WT）和突变型集胞藻细胞的动态变形，揭示了机械敏感（MS）通道的功能机制。该系统提供了一种监测单个完整细胞响应快速外部渗透变化的实时力学动力学的新方法；因此，该系统为准确描述细胞中MS通道的生理功能提供了新的机会。

关键词：微流控芯片力学性能动态变形单细胞液体交换

HTML PDF 收藏

Microfluidics for cell-cell interactions: A review

Rui Li,Xuefei Lv,Xingjian Zhang,Omer Saeed,Yulin Deng

《化学科学与工程前沿（英文）》 2016年第10卷第1期页码 90-98 doi: 10.1007/s11705-015-1550-2

摘要： Microfluidic chip has been applied in various biological fields owing to its low-consumption of reagents, high throughput, fluidic controllability and integrity. The well-designed microscale intermediary is also ideal for the study of cell biology. Particularly, microfluidic chip is helpful for better understanding cell-cell interactions. A general survey of recent publications would help to generalize the designs of the co-culture chips with different features. With ingenious and combinational utilization, the chips facilitate the implementation of some special co-culture models that are highly concerned in a different spatial and temporal way.

关键词： microfluidic chip co-culture cell-cell interactions review

HTML PDF 收藏

利用微流控技术应对COVID-19和其他肺部疾病的全球挑战

Yuliang Xie, Ryan Becker, Michael Scott, Kayla Bean, Tony Jun Huang

《工程（英文）》 2023年第24卷第5期页码 17-20 doi: 10.1016/j.eng.2022.01.003

HTML PDF 收藏

Microfluidic dual loops reactor for conducting a multistep reaction

Si Hyung Jin, Jae-Hoon Jung, Seong-Geun Jeong, Jongmin Kim, Tae Jung Park, Chang-Soo Lee

《化学科学与工程前沿（英文）》 2018年第12卷第2期页码 239-246 doi: 10.1007/s11705-017-1680-9

摘要： Precise control of each individual reaction that constitutes a multistep reaction must be performed to obtain the desired reaction product efficiently. In this work, we present a microfluidic dual loops reactor that enables multistep reaction by integrating two identical loop reactors. Specifically, reactants A and B are synthesized in the first loop reactor and transferred to the second loop reactor to synthesize with reactant C to form the final product. These individual reactions have nano-liter volumes and are carried out in a stepwise manner in each reactor without any cross-contamination issue. To precisely control the mixing efficiency in each loop reactor, we investigate the operating pressure and the operating frequency on the mixing valves for rotary mixing. This microfluidic dual loops reactor is integrated with several valves to realize the fully automated unit operation of a multistep reaction, such as metering the reactants, rotary mixing, transportation, and collecting the product. For proof of concept, CdSeZn nanoparticles are successfully synthesized in a microfluidic dual loops reactor through a fully automated multistep reaction. Taking all of these features together, this microfluidic dual loops reactor is a general microfluidic screening platform that can synthesize various materials through a multistep reaction.

关键词： microfluidics multistep reaction rotary mixing nanoparticle

HTML PDF 收藏

技术热点、前沿识别支持的2035技术清单调整方法——以机器人技术为例

林亨,周源,刘宇飞

《中国工程科学》 2017年第19卷第1期页码 124-132 doi: 10.15302/J-SSCAE-2017.01.018

摘要：

本文针对技术预见中关注度较高的技术热点、前沿识别和趋势分析问题，综合以往研究提出的成体系的和较为完善的分析方法，并以机器人技术为例，分析了机器人领域的技术热点和技术前沿以及发展趋势，为中国工程科技2035发展战略研究中技术清单的提出与技术产业布局提供了重要的数据支持。

关键词：技术预见技术热点技术前沿专利分析机器人技术

HTML PDF 收藏

中国环境工程科技2035技术预见研究

但智钢,史菲菲,王志增,王辉锋、张裴雷、郝吉明、段宁

《中国工程科学》 2017年第19卷第1期页码 80-86 doi: 10.15302/J-SSCAE-2017.01.012

摘要：

技术预见是制定科技发展战略和科技政策的重要基础，德尔菲调查是技术预见中最常用的方法。本研究通过文献分析、专家建议、会议讨论等方法，从大气污染防治、水污染防治、固体废弃物污染防治与资源化、土壤污染防治、生态保护与恢复、环境监测预警与风险控制、资源利用与清洁生产7个子领域提出我国环境工程领域的45项备选技术。根据德尔菲法的调查结果，初步筛选出2035年我国环境工程科技发展的关键技术、共性技术以及颠覆性技术，分析了技术实现时间、发展水平与制约因素，为未来20年我国环境工程科技发展战略和目标的制定提供参考。

关键词：环境工程科技技术预见德尔菲调查关键技术共性技术颠覆性技术

HTML PDF 收藏

航空技术的发展趋势和创新基地建设

张彦仲

《中国工程科学》 1999年第1卷第1期页码 19-23

摘要：

面对21世纪的需要，下一代航空器将飞得更快、尺寸更大、更经济安全、消耗资源更少。载客1 000人的大型飞机、高超音速飞机、微型无人机、地效飞机、倾转旋翼飞机等将交付使用。为减少污染和对石油的依赖，将采用替代燃料。飞机的经济性、安全性、环保性能将有成倍甚至成十倍地提高。面对挑战，必须加强航空技术创新基地建设。

关键词：航空技术发展趋势技术创新重点实验室

HTML PDF 收藏

Status of domestic gasification technology in China

Zhimin HUANG , Jiansheng ZHANG , Guangxi YUE ,

《能源前沿（英文）》 2009年第3卷第3期页码 330-336 doi: 10.1007/s11708-009-0021-1

摘要： Five domestic gasification technologies in China were presented and reviewed, including opposed multi-burner (OMB) gasification technology of coal water slurry (CWS), oxygen staged gasification technology, two-stage dry feed entrained flow gasification, pulverized coal gasification process of HT-L, and ash agglomerating fluidized bed gasification. The former four technologies belong to pressurized entrained flow gasification technology. The process description, technology characteristics, research and development process, performance indexes and commercialization progress of these technologies were mainly discussed.

关键词： domestic gasification technology research and development performance commercialization

HTML PDF 收藏

Computer aided process planning system based on workflow technology and integrated bill of material tree

LU Chun-guang, MENG Li-li

《机械工程前沿（英文）》 2006年第1卷第3期页码 305-312 doi: 10.1007/s11465-006-0039-6

摘要： It is extremely important for procedure of process design and management of process data for product life cycle in Computer Aided Process Planning (CAPP) system, but there are many shortcomings with traditional CAPP system in these respects. To solve these questions, application of workflow technology in CAPP system based on web-integrated Bill of Material (BOM) tree is discussed, and a concept of integrated BOM tree was brought forward. Taking integrated BOM as the thread, CAPP systematic technological process is analyzed. The function, system architecture, and implementation mechanism of CAPP system based on Browser/Server and Customer/Server model are expatiated. Based on it, the key technologies of workflow management device were analyzed. Eventually, the implementation mechanism of integrated BOM tree was analyzed from viewpoints of material information encoding, organization node design of integrated BOM tree, transformation from Engineering BOM (EBOM) to Process BOM(PBOM), and the programming implementation technology.

关键词： PBOM systematic technological implementation technology management workflow technology

HTML PDF 收藏

Digital technology-driven smart society governance mechanism and practice exploration

《工程管理前沿（英文）》 2023年第10卷第2期页码 319-338 doi: 10.1007/s42524-022-0200-x

摘要： A smart society is an advanced form of society following agricultural society, industrial society, and information society, with digital data processing system as its main carrier. However, the governance of a smart society still faces many challenges. In view of this problem, first, this research constructs a smart society governance modernization strategy. Second, the innovation mode of a society governance mechanism driven by digital technology is proposed, including the precise intellectual control of a digital twin, the intelligent ubiquitous sensing of the Internet of Things, the empowerment remodeling of a blockchain and the livelihood service of artificial intelligence. Third, this study systematically explores the practice of smart society governance modernization from the aspects of basic information platform construction, evaluation system construction, application demonstration of epidemic prevention and control driven by big data, support of spatial intelligence and artificial intelligence technology for people’s livelihood, smart campus, public resources, and data governance application demonstration to provide theoretical guidance for promoting digital technology innovation in the process of the governance of a smart society.

关键词： digital technology new infrastructure smart society governance system governance modernization